太阳成集团tyc234cc

黄成栋


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姓  名:

黄成栋

地  址:

安徽省合肥市中国科学技术大学生命科学学院附楼706

邮  编:

230027

电  话:

(0551)-63600743

电  邮:

huangcd@ustc.edu.cn

主  页:

https://biox.ustc.edu.cn/2017/0301/c699a167436/page.htm




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 教育与科研经历


2001年毕业于大连理工大学获得工科学士学位;2004年于中科院大连化学物理研究所获工科硕士学位;2010年于美国奥本大学化学系获生物化学博士学位。此后先后在石溪大学、罗格斯大学以及明尼苏达大学从事博士后研究。多年来一直从事生物核磁共振领域的研究,在Nature、PNAS、JACS等国际期刊上发表了系列文章,并在Annual Review of Biophysics杂志上撰写综述文章。


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 目前研究方向


应用生物核磁共振解析动态生物大分子的结构及功能机理


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 代表性论文

1.

Huang, Chengdong; Kalodimos, Charalampos, G. Structures of Large Protein Complexes by NMR. Annu. Rev. Biophys. (2017) 46,317-336.

2.

Huang, Chengdong; Rossi, Paolo; Saio, Tomohide; Kalodimos, Charalampos, G. Structural basis for the antifolding activity of a molecular chaperone. Nature. (2016) 537, 202-206.

3.

Rath, Poonam; Huang, Chengdong; Wang, Tao; Wang, Tianzhi; Li, Huilin; Prados-Rosales, Rafael; Elemento, Olivier; Casadevall, Arturo; Nathan, Carl F. Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA. (2013) 110(49), E4790-4797.

4.

Huang, Chengdong*; Li, Guangtao*; Lennarz, William J.Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission. (*Equal contribution) Proc. Natl. Acad. Sci. USA (2012) 109(25), 9792-9297.

5.

Li, Guangtao*; Huang, Chengdong*, Zhao, Gang; Lennarz, William J. Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97. (*Equal contribution) Proc. Natl. Acad. Sci. USA (2012), 109(10), 3737-3741.

6.

Huang, Chengdong; Bhaskaran, Rajagopalan; Mohanty, Smita. Eukaryotic N-glycosylation Occurs Via membrane-anchored C-terminal domain of Stt3p subunit of oligosaccharyl transferase. J. Biol. Chem. (2012) 287(39), 32450-32458.

7.

Huang, Chengdong; Mohanty, Smita. Challenging the Limit: NMR Assignment of a 31 kDa Monomeric Helical Membrane Protein. J. Am. Chem. Soc. (2010), 132, 3662–3663.

8.

Huang, Chengdong; Mohanty, Smita, Bannerjee, Monimoy. A novel method of production and biophysical characterization of C-terminal domain of Stt3p, the catalyzing subunit of yeast Oligosaccharyl Transferase. Biochemistry (2010), 49, 1115–1126.


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